Dr Arijit Bishnu is the best haemato- onchologist in Siliguri, with great skills and friendly nature.
CAR T-cell Therapy (Chimeric Antigen Receptor T-cell therapy) is a groundbreaking immunotherapy that harnesses the power of the body’s own immune system to fight hematologic cancers such as leukemia, lymphoma, and myeloma. The therapy involves collecting T-cells (a type of white blood cell) from the patient’s blood, genetically modifying them in a laboratory to express a chimeric antigen receptor (CAR) that recognizes cancer-specific antigens, and then reinfusing the modified T-cells back into the patient. This modification enables the T-cells to specifically target and kill cancer cells with greater precision and efficacy. CAR T-cell therapy has shown remarkable success in treating patients with refractory or relapsed blood cancers, especially in conditions like acute lymphoblastic leukemia (ALL) and diffuse large B-cell lymphoma (DLBCL), where traditional treatments have failed. For example, in some cases of ALL, CAR T-cells have resulted in complete remission for patients who previously had limited options. Despite its potential, CAR T-cell therapy can cause significant side effects, such as cytokine release syndrome (CRS), a systemic inflammatory response, and neurologic toxicities, which need careful monitoring and management by specialized medical teams.
CAR T-cell therapy is administered in a highly controlled setting, typically at specialized cancer treatment centers, and requires rigorous follow-up care. The treatment is tailored to each patient’s unique cancer profile, offering a personalized approach that has the potential to be curative. As research progresses, the scope of CAR T-cell therapy is expanding, with ongoing trials exploring its use in other hematologic malignancies and solid tumors, further solidifying its role as a transformative therapy in hematologic oncology.
Dr. Arijit Bishnu and his team use advanced diagnostics, such as genetic testing and molecular profiling, to determine whether targeted therapy is right for a patient. Treatment is then closely monitored and adjusted based on response and tolerance :
Medical History Review: Understanding your symptoms, lifestyle, and medical history to assess any underlying conditions that may be contributing to the menstrual issues.
Treatment of specific blood cancers - Used in conditions such as chronic myeloid leukemia (CML), chronic lymphocytic leukemia (CLL), certain lymphomas, and myeloproliferative neoplasms.
Molecular targeting - Focuses on proteins, genes, or cellular pathways that drive abnormal blood cell growth or survival.
Genetic testing required -Requires molecular diagnostics to identify the presence of targetable mutations or markers.
Fewer side effects than chemotherapy - Typically spares normal cells, leading to lower risk of hair loss, nausea, or widespread immune suppression.
Key advancement in personalized medicine - Allows hematologists to match treatment to each patient’s unique disease profile for optimal outcomes.
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